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kramper. Desuden kan der opstå en stærk trang til atter at indtage stoffet. Ved ophør af behandlingen skal dosis derfor nedtrappes gradvist for at undgå abstinenser. rapid smertebehandling med depotpræparater provides fejlagtigt kun som p.n. Patienten bliver ikke smertedækket optimalt og risikoen for komplikationer øges (gennembrudssmerter,